In order to explore the fracture mechanism of jointed Phyllite, the TAJW-2000 rock mechanics test system is used to carry out uniaxial compression tests on different joint inclination Phyllites. The influence of joint inclination of Phyllite failure mode is discussed, and the progressive failure process of Phyllite is studied. The test results show that the uniaxial compressive strength anisotropy of jointed Phyllite is remarkable. As the inclination increases, it exhibits a U-shaped change; When 30° ≤ α ≤ 75°, the tensile and shear failures along the joint inclination mainly occurs. the joint inclination controls the failure surface form of the Phyllite; The crack initial stress level of the joint Phyllite is 0.30-0.59σf, the crack failure stress level is 0.44-0.86σf. When α = 90°, the σcd value is the largest, and σcd with α = 90° can be used as the maximum reliable value of uniaxial compressive strength of Phyllite. Using the theory of fracture mechanics, it is analyzed that under uniaxial compression of the rock, the crack does not break along the original crack direction, but extends along the direction at a certain angle to the original crack. The joint effect coefficient is proposed to show the influence of the joint inclination on the uniaxial compressive strength of the phyllite. Both the test and simulation results show that when the joint inclination is 60°, the joint effect coefficient is the largest. The compressive strength is the smallest. Numerical simulation analyses the crack evolution law of phyllite under different joint inclination under uniaxial compression, which verifies that there are different failure modes of joint phyllite under uniaxial compression.