Nosocomial transmission of a blaVIM-2 carbapenemase integron between isolates of two different Pseudomonas species

Andrea C Büchler; Daniel Wüthrich; Melanie Wicki Jauslin; Adrian Egli; Andreas F Widmer

doi:10.1017/ice.2021.39

Nosocomial transmission of a bla_VIM-2 carbapenemase integron between isolates of two different Pseudomonas species

Infect Control Hosp Epidemiol. 2022 Feb;43(2):245-247. doi: 10.1017/ice.2021.39. Epub 2021 Feb 19.

Authors

Andrea C Büchler¹, Daniel Wüthrich^{2

3}, Melanie Wicki Jauslin¹, Adrian Egli^{2

3}, Andreas F Widmer¹

Affiliations

¹ Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland.
² Division of Clinical Bacteriology and Mycology, University Hospital Basel, Basel, Switzerland.
³ Applied Microbiology Research, Department of Biomedicine, University of Basel, Basel, Switzerland.

PMID: 33602379
DOI: 10.1017/ice.2021.39

Abstract

We report the first documented in-hospital patient-to-patient-transmission of a blaVIM-2 integron between isolates of Pseudomonas alcaligenes and P. aeruginosa. Molecular typing looking only for difference within species may fail to detect nosocomial transmission of resistance genes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents
Bacterial Proteins / genetics
Carbapenems
Cross Infection* / epidemiology
Humans
Integrons / genetics
Microbial Sensitivity Tests
Pseudomonas / genetics
Pseudomonas Infections* / epidemiology
Pseudomonas aeruginosa / genetics
beta-Lactamases / genetics

Substances

Anti-Bacterial Agents
Bacterial Proteins
Carbapenems
beta-Lactamases
carbapenemase