Soft Liver Phantom with a Hollow Biliary System

Ann Biomed Eng. 2021 Sep;49(9):2139-2149. doi: 10.1007/s10439-021-02726-x. Epub 2021 Feb 16.

Abstract

Hepatobiliary interventions are regarded as difficult minimally-invasive procedures that require experience and skills of physicians. To facilitate the surgical training, we develop a soft, high-fidelity and durable liver phantom with detailed morphology. The phantom is anatomically accurate and feasible for the multi-modality medical imaging, including computer tomography (CT), ultrasound, and endoscopy. The CT results show that the phantom resembles the detailed anatomy of real livers including the biliary ducts, with a spatial root mean square error (RMSE) of 1.7 ± 0.7 mm and 0.9 ± 0.2 mm for the biliary duct and the liver outer shape, respectively. The sonographic signals and the endoscopic appearance highly mimic those of the real organ. An electric sensing system was developed for the real-time quantitative tracking of the transhepatic puncturing needle. The fabrication method herein is accurate and reproducible, and the needle tracking system offers a robust and general approach to evaluate the centesis outcome.

Keywords: 3D printing; Biliary interventions; Centesis; Electrical sensing; Interventional surgical training; Liver model; Organ phantom; Ultrasound imaging.

MeSH terms

  • Biliary Tract / diagnostic imaging*
  • Endoscopy
  • Liver / diagnostic imaging*
  • Models, Anatomic
  • Phantoms, Imaging*
  • Tomography, X-Ray Computed
  • Ultrasonography