Recent findings and future directions of grafted gum karaya polysaccharides and their various applications: A review

Carbohydr Polym. 2021 Apr 15:258:117687. doi: 10.1016/j.carbpol.2021.117687. Epub 2021 Jan 23.

Abstract

Gum karaya is a polysaccharide that has several industrial applications in the pharmaceutical, food, and environmental fields owing to its hydrophilic, anionic, and biocompatible nature. Gum karaya and its modified forms have been assessed for drug delivery, wastewater treatment, and food industry applications. This review provides a comprehensive overview of various synthetic methods of modification of gum karaya, such as grafting initiated through free radical, microwave-assisted grafting, radiation-assisted, and enzyme-assisted modification methods. In addition, the review outlines collective industrial applications of modified gum karaya in drug delivery systems, removal of heavy atoms, dyes, food, and other biological activities, and suggests possible prospects for gum karaya modification and their remarkable industrial applications.

Keywords: Bio-medication and environmental applications; Grafting and crosslinking; Gum karaya; Modified polymeric material.

Publication types

  • Review

MeSH terms

  • Adsorption
  • Animals
  • Anti-Infective Agents / pharmacology
  • Antineoplastic Agents / pharmacology
  • Chemistry, Pharmaceutical / methods
  • Coloring Agents / isolation & purification
  • Drug Carriers / chemistry*
  • Drug Delivery Systems
  • Drug Design*
  • Free Radicals
  • Humans
  • Hydrogels / chemistry
  • Hydrogen-Ion Concentration
  • Ions
  • Karaya Gum / chemistry*
  • Metals / chemistry
  • Metals, Heavy / isolation & purification
  • Microwaves
  • Polymers / chemistry
  • Polysaccharides / chemistry*
  • Water Purification / methods*

Substances

  • Anti-Infective Agents
  • Antineoplastic Agents
  • Coloring Agents
  • Drug Carriers
  • Free Radicals
  • Hydrogels
  • Ions
  • Metals
  • Metals, Heavy
  • Polymers
  • Polysaccharides
  • Karaya Gum