Simultaneous isolation and selective encapsulation of volatile compounds from essential oil during electrospraying of β-Cyclodextrin

Abstract

This study's primary purpose was to develop a new technique to stabilize high value-added bioactive volatile compounds present in essential oils to ensure their usability as chemical raw materials with enhanced stability. Selective isolation and encapsulation of various volatile compounds by changing the electrospraying process parameter, including voltage, flow rate, and β-Cyclodextrin concentration, were attributed to the formation of inclusion complexes between β-cyclodextrin and volatile compounds. Investigations regarding the effects of independent process variables on simultaneous isolation and selective encapsulation of volatile compounds during electrospraying of β-cyclodextrins were carried out mainly with TLC analyses. The TLC analyses were confirmed with GC, GC-MS, and ¹H NMR analyses. It was possible to obtain nanoparticles with an average particle size between 25-160 nm with the designed system. Obtained data revealed that isolation and encapsulation of cumin aldehyde, camphene, isoborneol, and hexadecanoic acid, benzyl benzoate from labdanum essential oil were successfully achieved.

Keywords: Benzyl benzoate (CID: 2345); Camphene (CID:6616); Cumin aldehyde (CID: 326); Encapsulation; Hexadecanoic acid (CID: 985); Isoborneol (CID: 6321405); Isolation; Labdanum essential oil; Stabilization; β-Cyclodextrin; β-Cyclodextrin (CID:444041).