Comprehensive two-dimensional gas chromatography as a boosting technology in food-omic investigations

J Sep Sci. 2021 Apr;44(8):1592-1611. doi: 10.1002/jssc.202100017. Epub 2021 Mar 19.

Abstract

This review focuses on the role that comprehensive two-dimensional gas chromatography can play within the investigation workflows of food-omics and related disciplines and subdisciplines, including food metabolomics, nutrimetabolomics, sensomics, and food safety. After a short introductory survey, discussing the intriguing context of system biology and integrationist approaches of investigation, the concepts of analytical dimensions and the key characteristics of comprehensive two-dimensional gas chromatography are introduced. Through a selection of relevant examples, the boosting role of comprehensive two-dimensional gas chromatography within food-omics is described, providing to the reader evidence of how comprehensive multidimensional separations based platforms have introduced new concepts and tools in the analytical measurement of complex biological samples.

Keywords: comprehensive two-dimensional gas chromatography; food metabolomics; food safety; nutrimetabolomics; sensomics.

Publication types

  • Review

MeSH terms

  • Chromatography, Gas
  • Food Analysis*
  • Food Contamination / analysis*
  • Food Safety
  • Metabolomics
  • Volatile Organic Compounds / analysis*
  • Volatile Organic Compounds / metabolism

Substances

  • Volatile Organic Compounds