Robotics, microfluidics, nanotechnology and AI in the synthesis and evaluation of liposomes and polymeric drug delivery systems

Drug Deliv Transl Res. 2021 Apr;11(2):345-352. doi: 10.1007/s13346-021-00929-2. Epub 2021 Feb 13.

Abstract

The field of nanotechnology and personalised medicine is undergoing drastic changes in the approach and efficiency of experimentation. The COVID-19 pandemic has spiralled into mass stagnation of major laboratories around the globe and led to increased investment into remote systems for nanoparticle experiments. A significant number of laboratories now operate using automated systems; however, the extension to nanoparticle preparation and artificial intelligence-dependent databases holds great translational promise. The strive to combine automation with artificial intelligence (AI) grants the ability to optimise targeted therapeutic nanoparticles for unique cell types and patients. In this perspective, the current and future trends of automated approaches to nanomedicine synthesis are discussed and compared with traditional methods.

Keywords: Artificial intelligence; Automation; Microfluidics; Nanotechnology; Personalised medicine.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Artificial Intelligence
  • COVID-19 Drug Treatment*
  • Drug Delivery Systems
  • Humans
  • Lab-On-A-Chip Devices
  • Liposomes / chemical synthesis*
  • Liposomes / chemistry
  • Nanoparticles
  • Precision Medicine
  • Robotics

Substances

  • Liposomes