p value variability and subgroup testing

Eur J Nutr. 2021 Dec;60(8):4203-4206. doi: 10.1007/s00394-021-02498-z. Epub 2021 Feb 13.

Abstract

This article discusses the variability and randomness of p values, the most widely used currency of evidence in nutritional and health studies. One implication of this, the importance of always testing interaction terms when subgroups are examined and presented separately is also discussed.

Keywords: Interaction; Subgroup; p value.