A new medication, a new toxidrome - A case report of anticholinergic wipe toxicity due to improper medication use

Am J Emerg Med. 2021 Aug:46:797.e1-797.e2. doi: 10.1016/j.ajem.2021.01.060. Epub 2021 Jan 29.

Abstract

We describe a case of a young female who presented to the emergency department with 4 days of progressive myopia, dry mouth, anhidrosis and urinary hesitancy due to overuse of a new topical anticholinergic wipes, glycopyrronium tosylate (GT). In the United States medication misuse accounts for nearly 10% of pediatric emergency visits with 65% of these visits considered to be preventable [1]. Being familiar with new medications and their side effect profiles can prevent unnecessary or harmful interventions.

Keywords: Overdose; Pediatrics; Pharmacology; Toxicology.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Adolescent
  • Axilla
  • Cholinergic Antagonists / administration & dosage
  • Cholinergic Antagonists / toxicity*
  • Emergency Service, Hospital
  • Female
  • Glycopyrrolate / administration & dosage
  • Glycopyrrolate / toxicity*
  • Hoarseness / chemically induced
  • Humans
  • Hyperhidrosis / drug therapy
  • Mydriasis / chemically induced
  • Urinary Incontinence / chemically induced

Substances

  • Cholinergic Antagonists
  • glycopyrronium tosylate
  • Glycopyrrolate