Anti-tobacco mosaic virus (TMV) activity of chemical constituents from the seeds of Sophora tonkinensis

J Asian Nat Prod Res. 2021 Jul;23(7):644-651. doi: 10.1080/10286020.2021.1886089. Epub 2021 Feb 15.

Abstract

Two new compounds, including one new arylbenzofuran (1) and one new pterocarpanoid (2), along with nine known ones, were isolated from the seeds of Sophora tonkinensis. The structures of the new compounds were elucidated based on a comprehensive spectroscopic data analysis. Compounds 2 and 3 exhibited good anti-tobacco mosaic virus (TMV) activities with the protective inhibition rate of 69.62% and 68.72% respectively, at concentration of 100 μg/ml.

Keywords: Leguminosae; Sophora tonkinensis Gagnep.; anti-TMV; sophtonseedlin A; sophtonseedlin B.

MeSH terms

  • Antiviral Agents / pharmacology
  • Molecular Structure
  • Seeds
  • Sophora*
  • Tobacco Mosaic Virus*

Substances

  • Antiviral Agents