Recent progress in determination of ochratoxin a in foods by chromatographic and mass spectrometry methods

Crit Rev Food Sci Nutr. 2022;62(20):5444-5461. doi: 10.1080/10408398.2021.1885340. Epub 2021 Feb 13.

Abstract

Ochratoxin A is a highly toxic mycotoxin and has posed great threat to human health. Due to its serious toxicity and wide contamination, great efforts have been made to develop reliable determination methods. In this review, analytical methods are comprehensively summarized in terms of sample preparation strategy and instrumental analysis. Detailed method is described according to the food commodities in the order of cereal, wine, coffee, beer, cocoa, dried fruit and spice. This review mainly focuses on the recent advances, especially reported in the last decade. At last, challenges and perspectives are also discussed to achieve better advancement and promote practical application in this field.

Keywords: analytical methods; food safety; ochratoxin A; sample preparation.

Publication types

  • Review

MeSH terms

  • Chromatography, High Pressure Liquid / methods
  • Food Contamination* / analysis
  • Humans
  • Mass Spectrometry
  • Ochratoxins*

Substances

  • Ochratoxins
  • ochratoxin A