Cutaneous manifestations of antiphospholipid syndrome

Abstract

Antiphospholipid syndrome (APS) is an acquired thrombophilic disorder in which autoantibodies are produced against a variety of phospholipids and phospholipid-binding proteins. The purpose of this article is to review cutaneous findings in patients with APS diagnosis. An overview regarding prevalence, description, pathogenesis and histopathology, are described for cutaneous manifestations of APS.

Keywords: Antiphospholipid syndrome; antibodies; anticardiolipin necrosis; clinical dermatology; livedo; lupus anticoagulant; vasculitis.