Successful management of donor-acquired fat embolism after lung transplantation

Interact Cardiovasc Thorac Surg. 2021 Jun 28;33(1):158-160. doi: 10.1093/icvts/ivab051.

Abstract

Fat embolism is a serious complication in patients with multiple traumatic injuries. It is often asymptomatic during the first hours of resuscitation, thus remains underdiagnosed in patients who progress to brain death. Lung transplantation issued from such grafts can lead to severe lung primary graft dysfunction, the management of which is deemed difficult. Herein, we report a successful management of donor-acquired fat embolism syndrome after lung transplant in a 22 years old woman for cystic fibrosis. Fat embolism was suspected because of the donor's traumatic injuries and confirmed by histopathological analysis. An immediate postoperative primary graft dysfunction was successfully managed with veno-arterial extracorporeal membrane oxygenation. The patient is alive 31 months after surgery.

Keywords: Extracorporeal membrane oxygenation; Lung transplantation; Primary graft dysfunction fat embolism.

MeSH terms

  • Adult
  • Embolism, Fat* / diagnostic imaging
  • Embolism, Fat* / etiology
  • Female
  • Humans
  • Lung Transplantation* / adverse effects
  • Primary Graft Dysfunction* / etiology
  • Primary Graft Dysfunction* / therapy
  • Pulmonary Embolism*
  • Tissue Donors
  • Young Adult