RETRACTED:BMSCs-derived exosomal microRNA-150-5p attenuates myocardial infarction in mice

Int Immunopharmacol. 2021 Apr:93:107389. doi: 10.1016/j.intimp.2021.107389. Epub 2021 Feb 11.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Concern was raised about the reliability of the Western blot results in Figs. 2B and 7B, which appear to have the same eyebrow shaped phenotype as many other publications tabulated here (https://docs.google.com/spreadsheets/d/149EjFXVxpwkBXYJOnOHb6RhAqT4a2llhj9LM60MBffM/edit#gid=0 [docs.google.com]). Concerns were also raised over the provenance of the flow cytometry plots in Fig. 1F. The journal requested the corresponding author comment on these concerns and provide the raw data. However, the authors were not responsive to the request for comment. Since original data could not be provided, the overall validity of the results could not be confirmed. Therefore, the Editor-in-Chief decided to retract the article.

Keywords: Bone marrow mesenchymal stem cells-derived exosomes; MicroRNA-150-5p; Myocardial infarction.

Publication types

  • Retracted Publication

MeSH terms

  • Animals
  • Apoptosis
  • Cells, Cultured
  • Exosomes / genetics*
  • Male
  • Mesenchymal Stem Cells*
  • Mice
  • Mice, Inbred C57BL
  • MicroRNAs*
  • Myocardial Infarction / therapy*
  • Myocardium / metabolism
  • Myocytes, Cardiac

Substances

  • MicroRNAs
  • Mirn150 microRNA, mouse