Genome engineering for crop improvement and future agriculture

Cell. 2021 Mar 18;184(6):1621-1635. doi: 10.1016/j.cell.2021.01.005. Epub 2021 Feb 12.

Abstract

Feeding the ever-growing population is a major challenge, especially in light of rapidly changing climate conditions. Genome editing is set to revolutionize plant breeding and could help secure the global food supply. Here, I review the development and application of genome editing tools in plants while highlighting newly developed techniques. I describe new plant breeding strategies based on genome editing and discuss their impact on crop production, with an emphasis on recent advancements in genome editing-based plant improvements that could not be achieved by conventional breeding. I also discuss challenges facing genome editing that must be overcome before realizing the full potential of this technology toward future crops and food production.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Agriculture*
  • Crops, Agricultural / genetics*
  • Genetic Engineering*
  • Genome, Plant*
  • Plant Breeding
  • Quantitative Trait Loci / genetics