Abstract
TRPC4 ion channel was reported to be regulated by small molecular inhibitors and calmodulin. We discuss these findings in the context of other members of TRPC subfamily modulated by different stimulants.
Keywords:
Calmodulin; Small molecular modulator; TRPC4.
Copyright © 2021 Elsevier Ltd. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Binding Sites / drug effects
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Binding Sites / physiology
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Calmodulin / metabolism*
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Calmodulin / pharmacology
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Humans
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Protein Structure, Secondary
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TRPC Cation Channels / antagonists & inhibitors*
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TRPC Cation Channels / chemistry
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TRPC Cation Channels / metabolism*
Substances
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Calmodulin
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TRPC Cation Channels
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TRPC4 ion channel