Comparison of an upgraded optical biometer with 2 validated optical biometers

J Cataract Refract Surg. 2021 Jul 1;47(7):859-864. doi: 10.1097/j.jcrs.0000000000000541.

Abstract

Purpose: The Revo NX is a new optical biometer, based on spectral-domain optical coherence tomography and able to obtain high-definition scans of both the anterior and posterior segment of the eye. A previous study found that its measurements of axial length (AL) were not interchangeable with those provided by a validated optical biometer; so, the manufacturer updated the instrument to improve agreement of AL values. This study aimed to prospectively compare the measurements by the updated Revo NX (version 9.5.0, biometry module) with those by 2 validated devices, the IOLMaster 700 and Lenstar LS-900.

Setting: Optopol Technologies, Zawiercie, Poland.

Design: Prospective evaluation of diagnostic test.

Methods: Comparison between the devices was performed using repeated measures analysis of variance (ANOVA) with Bonferroni posttest, correlation coefficients, and the Bland-Altman method.

Results: The investigation evaluated the results of 63 patients. For AL, anterior chamber depth (ACD), and lens thickness (LT), the differences were not clinically significant because they were less than 0.01 mm. Repeated measures ANOVA, however, detected a statistically significant difference for AL (P < .0001) and central corneal thickness (P < .0001) but not for ACD (P = .0630) or LT (P = .2667). The results obtained with all 3 biometers manifested a high level of agreement in the Bland-Altman analysis and very strong correlation.

Conclusions: The measurements by the updated Revo NX had high agreement with the other optical biometers; a clear improvement was detected than the previous analysis between the original Revo NX (version 8.0.3) and the Lenstar LS-900.

MeSH terms

  • Anterior Chamber* / anatomy & histology
  • Anterior Chamber* / diagnostic imaging
  • Axial Length, Eye* / anatomy & histology
  • Biometry
  • Cornea / anatomy & histology
  • Humans
  • Interferometry
  • Prospective Studies
  • Reproducibility of Results
  • Tomography, Optical Coherence