Assessing Brain Capillaries in Coronavirus Disease 2019

David W Nauen; Jody E Hooper; C Matthew Stewart; Isaac H Solomon

doi:10.1001/jamaneurol.2021.0225

Assessing Brain Capillaries in Coronavirus Disease 2019

JAMA Neurol. 2021 Jun 1;78(6):760-762. doi: 10.1001/jamaneurol.2021.0225.

Authors

David W Nauen¹, Jody E Hooper¹, C Matthew Stewart², Isaac H Solomon³

Affiliations

¹ Department of Pathology, Johns Hopkins University, Baltimore, Maryland.
² Department of Otolaryngology, Johns Hopkins University, Baltimore, Maryland.
³ Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.

Abstract

This case series analyzes brains from autopsies of patients who died of coronavirus disease 2019 as confirmed by nucleic acid test and with severe pulmonary pathology.

MeSH terms

Aged
Aged, 80 and over
Autopsy
Blood Platelets / pathology
Blood-Brain Barrier
Brain / pathology*
COVID-19 / pathology*
Capillaries / pathology*
Cerebral Cortex / pathology
Cerebrovascular Circulation
Female
Humans
Male
Megakaryocytes / pathology
Middle Aged