Microscopic Polyangiitis Presenting with Splenic Infarction: A Case Report

Medicina (Kaunas). 2021 Feb 9;57(2):157. doi: 10.3390/medicina57020157.

Abstract

Microscopic polyangiitis (MPA) is an anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). The splenic involvement in AAV is known to be rare, and that in MPA has not been reported to date. A 74-year-old woman was admitted owing to left arm numbness and weakness. The patient was diagnosed as MPA with vasculitic neuropathy. Her abdominal computed tomography (CT) revealed splenic infarction incidentally. The splenic infarction had been resolved at follow-up CT after treatment. If splenic involvement of MPA was not considered, treatment may have been delayed in order to differentiate other diseases. Herein, I report the first case of splenic involvement of MPA.

Keywords: ANCA-associated vasculitis; MPA; splenic infarction.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis*
  • Antibodies, Antineutrophil Cytoplasmic
  • Female
  • Humans
  • Microscopic Polyangiitis* / complications
  • Microscopic Polyangiitis* / diagnosis
  • Microscopic Polyangiitis* / drug therapy
  • Peripheral Nervous System Diseases*
  • Splenic Infarction* / diagnostic imaging
  • Splenic Infarction* / etiology

Substances

  • Antibodies, Antineutrophil Cytoplasmic