Rare cause of acute abdomen-cocaine-induced small intestinal perforation with coexisting lower gastrointestinal bleed: an unusual presentation

BMJ Case Rep. 2021 Feb 10;14(2):e239981. doi: 10.1136/bcr-2020-239981.

Abstract

Cocaine, an alkaloid, is an addictive drug and its abuse as a recreational drug is on the increasing side with its associated complications. Gastrointestinal complications, after cocaine abuse, are less known and need to be addressed since the abuse is on the rise and the existing evidence is scarce. We report a case of a 22-year-old male patient who presented with abdominal pain following a cocaine injection. On examination, signs of peritonitis were noted and laparotomy revealed a 2×1 cm perforation in the distal ileum. The unhealthy intestinal segment was resected and taken out as a double-barrel ileostomy. The patient had an episode of severe lower gastrointestinal bleeding on postoperative day 6. CT and colonoscopy revealed signs of ischaemic bowel and tissue biopsy showed oedematous, inflamed and haemorrhagic bowel mucosa. The patient was managed conservatively and is doing well under follow-up in a de-addiction centre.

Keywords: drugs misuse (including addiction); gastrointestinal surgery.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cocaine-Related Disorders / complications*
  • Gastrointestinal Hemorrhage / chemically induced*
  • Gastrointestinal Hemorrhage / surgery*
  • Humans
  • Intestinal Perforation / chemically induced*
  • Intestinal Perforation / surgery*
  • Male
  • Rare Diseases / diagnosis*
  • Rare Diseases / surgery*
  • Treatment Outcome
  • Young Adult