Myeloid malignancies with 5q and 7q deletions are associated with extreme genomic complexity, biallelic TP53 variants, and very poor prognosis

Blood Cancer J. 2021 Feb 8;11(2):18. doi: 10.1038/s41408-021-00416-4.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Chromosome Deletion
  • Chromosomes, Human, Pair 5 / genetics*
  • Chromosomes, Human, Pair 7 / genetics*
  • Female
  • Gene Deletion
  • Humans
  • Leukemia, Myeloid, Acute / diagnosis
  • Leukemia, Myeloid, Acute / genetics*
  • Male
  • Middle Aged
  • Polymorphism, Single Nucleotide
  • Prognosis
  • Tumor Suppressor Protein p53 / genetics*
  • Young Adult

Substances

  • TP53 protein, human
  • Tumor Suppressor Protein p53