Diagnosis, Management, and Treatment Options: A Cervical Spine Osteochondroma Meta-Analysis

World Neurosurg. 2021 May:149:215-225.e6. doi: 10.1016/j.wneu.2021.01.148. Epub 2021 Feb 6.

Abstract

Osteochondroma is described as a capped benign bony neoplasm that forms on the outer surface of bone. These tumors affect nearly 6 million people per year. Although osteochondromas most often involve the appendicular skeleton, many involve the spine, with many cases located in the cervical spine. When osteochondromas involve the spine, they can present with a variety of symptoms, including pain, radiculopathy, and myelopathy, which may necessitate surgical treatment. Spinal osteochondromas can be classified into 2 types: multiple osteochondromas in the context of patients with multiple hereditary exostosis (MHE) and solitary osteochondroma or solitary exostosis (SE). Previous reviews have captured only some of the available literature on cervical osteochondromas and have generally focused on either SE or those associated with MHE. The purpose of our review was to provide an extensive review of all previously reported cervical osteochondromas and to compare osteochondroma characteristics, clinical presentation, and outcomes in the context of MHE and SE.

Keywords: Cervical spine; Exostosis; Multiple hereditary exostosis; Osteochondroma; Solitary exostosis; Spine oncology; Spine tumor.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Cervical Vertebrae / pathology
  • Cervical Vertebrae / surgery*
  • Disease Management*
  • Humans
  • Osteochondroma / diagnosis*
  • Osteochondroma / surgery*
  • Spinal Neoplasms / diagnosis*
  • Spinal Neoplasms / surgery*
  • Treatment Outcome