A Rare Case of von Willebrand Disease Presenting as Hemolacria and Literature Review

J Pediatr Hematol Oncol. 2021 Apr 1;43(3):101-103. doi: 10.1097/MPH.0000000000002077.

Abstract

Hemolacria is a rare condition that causes a person to produce tears that are partially composed of blood. It can be a presenting feature of certain ocular and systemic conditions. Here, the authors describe an interesting case of a 12-year-old boy with an underlying beta-thalassemia trait, who presented with a 2-day history of bilateral blood-stained tears, and an episode of epistaxis. Ocular examination was normal, and syringing showed no nasolacrimal duct blockage. Systemic examination was unremarkable. Laboratory investigations confirmed type 2 von Willebrand disease. Management of hemolacria remains a clinical challenge given the rare occurrence of the disease. In this case report, the authors discuss the differential diagnosis and management approach to hemolacria.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child
  • Epistaxis / blood
  • Epistaxis / complications
  • Epistaxis / diagnosis
  • Humans
  • Male
  • Rare Diseases / blood
  • Rare Diseases / complications
  • Rare Diseases / diagnosis
  • Tears* / chemistry
  • beta-Thalassemia / blood
  • beta-Thalassemia / complications
  • beta-Thalassemia / diagnosis
  • von Willebrand Diseases / blood
  • von Willebrand Diseases / complications
  • von Willebrand Diseases / diagnosis*