Objective: To compare the therapeutic effect between acupuncture combined with ibuprofen sustained-release capsule and simple ibuprofen sustained-release capsule on chronic pelvic pain (CPP) after pelvic inflammatory disease (PID).
Methods: A total of 144 patients were randomized into an observation group (72 cases, 10 cases dropped off) and a control group (72 cases, 9 cases dropped off). Ibuprofen sustained-release capsule was given orally in the control group, one capsule a time. On the basis of the treatment in the control group, acupuncture was applied at Guanyuan (CV 4), Shuidao (ST 28), Guilai (ST 29), Shenshu (BL 23) and Ciliao (BL 32), and Shuidao (ST 28), Guilai (ST 29), Shenshu (BL 23) and Ciliao (BL 32) were connected to electroacupuncture in the observation group. The treatment was given 10 days before menstruation, once a day for 3 menstrual cycles in both groups, and the follow-up was adopted 3 menstrual cycles after treatment. The visual analogue scale (VAS) scores of hypogastrium and lumbosacral region before treatment, after treatment, and at the follow-up, the score of local signs and the score of World Health Organization quality of life questionnaire-brief version (WHOQOL-BREF) before and after treatment were observed in the both groups.
Results: After treatment and at the follow-up, the VAS scores of hypogastrium and lumbosacral region were decreased compared before treatment in both groups (P<0.05), and those in the observation group were lower than the control group (P<0.05). After treatment, except for the score of uterosacral ligament tenderness in the control group, the scores of local signs were decreased compared before treatment in both groups (P<0.05), and the score of uterine appendages tenderness, the total score of local signs in the observation group were lower than the control group (P<0.05). Compared before treatment, the physiological scores of WHOQOL-BREF were increased in both groups (P<0.05), the scores of psychology, social relations and environment were increased in the observation group (P<0.05), and the physiological score was higher than the control group (P<0.05).
Conclusion: Acupuncture combined with ibuprofen sustained-release capsule can effectively improve the symptoms, signs and quality of life in patients with CPP after PID, the therapeutic effect is superior to simple ibuprofen sustained-release capsule.
目的：比较针刺联合布洛芬缓释胶囊与单纯口服布洛芬缓释胶囊治疗盆腔炎性疾病（PID）后遗症慢性盆腔痛（CPP）的疗效。方法：将144 例患者随机分为观察组（72例，脱落10例）和对照组（72例，脱落9例）。对照组予口服布洛芬缓释胶囊治疗，每次1粒；观察组在对照组基础上行针刺治疗，穴取关元、水道、归来、肾俞、次髎，其中水道、归来、肾俞、次髎行电针疗法。两组均于月经来潮前10 d开始治疗，每日1次，每个月经周期治疗10 d，共治疗3个月经周期，随访3个月经周期。记录两组患者治疗前后及随访时下腹部、腰骶部视觉模拟量表（VAS）评分和治疗前后局部体征评分、生活质量量表（WHOQOL-BREF）评分。结果：与治疗前比较，两组患者治疗后及随访时下腹部、腰骶部VAS评分均降低（P<0.05），且观察组患者治疗后及随访时VAS评分均低于对照组（P<0.05）。与治疗前比较，除对照组宫骶韧带触痛评分外，两组治疗后局部体征评分均降低（P<0.05），且观察组附件区压痛评分及局部体征总评分均低于对照组（P<0.05）。与治疗前比较，两组WHOQOL-BREF生理领域评分均升高（P<0.05），观察组心理、社会关系、环境领域评分升高（P<0.05），且观察组生理领域评分高于对照组（P<0.05）。结论：针刺联合布洛芬缓释胶囊可有效改善盆腔炎性疾病所致慢性盆腔痛患者疼痛症状、体征，提高其生活质量，其疗效优于单纯口服布洛芬缓释胶囊。.
Keywords: acupuncture; chronic pelvic pain; pain; pelvic inflammatory disease; quality of life; randomized controlled trial (RCT).