Surgery and dose-escalated radiotherapy for a de novo intracranial squamous cell carcinoma of the cerebellopontine angle

Layth Mula-Hussain; Julia Malone; Marlise P Dos Santos; Fahad Alkherayf; John Sinclair; Shawn Malone

doi:10.1016/j.ctro.2021.01.010

Surgery and dose-escalated radiotherapy for a de novo intracranial squamous cell carcinoma of the cerebellopontine angle

Clin Transl Radiat Oncol. 2021 Jan 27:27:99-102. doi: 10.1016/j.ctro.2021.01.010. eCollection 2021 Mar.

Authors

Layth Mula-Hussain¹, Julia Malone¹, Marlise P Dos Santos², Fahad Alkherayf³, John Sinclair³, Shawn Malone¹

Affiliations

¹ Radiation Oncology Division, The Ottawa Hospital - University of Ottawa, Ottawa, ON, Canada.
² Department of Medical Imaging, The Ottawa Hospital - University of Ottawa, and Ottawa Hospital Research Institute, Ottawa, ON, Canada.
³ Neurosurgery Division, The Ottawa Hospital - University of Ottawa, Ottawa, ON, Canada.

Abstract

We report an extremely rare case of de novo intracranial squamous cell carcinoma of the cerebellopontine angle. The patient underwent craniotomy for debulking of the lesion to relieve mass effect on the brainstem and to establish a tissue diagnosis. Cancer staging revealed no other primary cancers and no evidence of metastatic disease. Postoperatively, he received image-guided intensity-modulated radiotherapy to the tumor bed followed by fractionated radiosurgery boost to the gross residual disease for a total average dose of 7000 cGy. He had a complete response to radiation and remains 42-months' disease-free post-treatment.

Publication types

Case Reports