Are Your Mitochondria Ready for a Space Odyssey?

Abstract

Anticipating very long space trips, da Silveira et al. performed pan-omic analyses on in-flight samples from astronauts, mice, and cells. Results revealed major mitochondrial dysfunctions responsible for alterations in metabolism, immunity, and circadian rhythm, which should prompt the evaluation of countermeasures to reduce the risks of future space odysseys, especially toward the planet Mars.

Keywords: genome; mitochondria; omics; space odyssey.