Allogeneic simple limbal epithelial transplantation: an appropriate treatment for bilateral stem cell deficiency

BMJ Case Rep. 2021 Feb 5;14(2):e239998. doi: 10.1136/bcr-2020-239998.

Abstract

A 39-year-old man presented with both eyes limbal stem cell deficiency status post chemical injury. He was managed initially with topical medications to subside the ocular surface inflammation. Over the course of subsequent visits, the fibrovascular pannus over the cornea gradually progressed, leading to further diminution of vision in left eye more than right eye. Since, the ocular surface was wet, the patient committed for lifelong immunosuppression and his brother consented to donate healthy limbal tissue; he underwent living-related allogeneic simple limbal epithelial transplantation in the left eye.

Keywords: anterior chamber; ophthalmology.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cell Transplantation / methods*
  • Epithelium / transplantation*
  • Eye Burns / drug therapy
  • Eye Burns / surgery*
  • Humans
  • Limbus Corneae / cytology*
  • Male
  • Transplantation, Homologous
  • Visual Acuity