IFN Stimulates ACE2 Expression in Pediatric Airway Epithelial Cells

Am J Respir Cell Mol Biol. 2021 Apr;64(4):515-518. doi: 10.1165/rcmb.2020-0352LE.

Authors

Kyle Salka^{1

2}, Karima Abutaleb^{1

2}, Elizabeth Chorvinsky^{1

2}, Girija Thiruvengadam^{1

2}, Maria Arroyo^{1

2}, Jose L Gomez³, Maria J Gutierrez⁴, Dinesh K Pillai^{1

2}, Jyoti K Jaiswal^{1

2}, Gustavo Nino^{1

2}

Affiliations

¹ Children's National Hospital Washington, DC.
² George Washington University Washington, DC.
³ Yale University School of Medicine New Haven, Connecticut and.
⁴ Johns Hopkins University Baltimore, Maryland.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

Angiotensin-Converting Enzyme 2 / biosynthesis*
Angiotensin-Converting Enzyme 2 / genetics
Cells, Cultured
Enzyme Induction
Epithelial Cells / drug effects*
Epithelial Cells / enzymology
Female
Humans
Infant
Interferon-gamma / pharmacology*
Male
Nasal Mucosa / drug effects*
Nasal Mucosa / enzymology
Poly I-C / pharmacology*

Substances

Interferon-gamma
ACE2 protein, human
Angiotensin-Converting Enzyme 2
Poly I-C

Grants and funding