Electrospun Nanofibers for Cancer Therapy

Adv Exp Med Biol. 2021:1295:163-190. doi: 10.1007/978-3-030-58174-9_8.

Abstract

Lately, a remarkable progress has been recorded in the field of electrospinning for the preparation of numerous types of nanofiber scaffolds. These scaffolds present some remarkable features including high loading capacity and encapsulation efficiency, superficial area and porosity, potential for modification, structure for the co-delivery of various therapies, and cost-effectiveness. Their present and future applications for cancer diagnosis and treatment are promising and pioneering. In this chapter we provide a comprehensive overview of electrospun nanofibers (ESNFs) applications in cancer diagnosis and treatment, covering diverse types of drug-loaded electrospun nanofibers.

Keywords: Biosensors; Cancer diagnosis; Cell capture; Chemosensors; Drug carrier; Electrospun fibers; Gas sensors; Immunosensor; Immunotherapy; Intelligent cancer therapy; Switchable drug release; Synergistic therapy.

Publication types

  • Review

MeSH terms

  • Humans
  • Nanofibers*
  • Neoplasms* / diagnosis
  • Neoplasms* / drug therapy
  • Tissue Engineering