Nausea and the Brain: The Chemoreceptor Trigger Zone Enters the Molecular Age

Wenfei Han; Ivan E de Araujo

doi:10.1016/j.neuron.2021.01.004

Nausea and the Brain: The Chemoreceptor Trigger Zone Enters the Molecular Age

Neuron. 2021 Feb 3;109(3):391-393. doi: 10.1016/j.neuron.2021.01.004.

Authors

Wenfei Han¹, Ivan E de Araujo²

Affiliations

¹ Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
² Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Pharmacology and Therapeutics Discovery Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: Ivan.DeAraujo@mssm.edu.

PMID: 33539771
DOI: 10.1016/j.neuron.2021.01.004

Abstract

Area postrema in brainstem has long been known to trigger emesis by detecting blood-borne toxins and pathogens. In this issue, Zhang and colleagues provide a single-cell molecular atlas of this region, opening new possibilities for harnessing its neurons in vivo.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Area Postrema*
Brain Stem
Humans
Nausea*
Neurons
Vomiting