Surveillance of COVID-19-Associated Multisystem Inflammatory Syndrome in Children, South Korea

Emerg Infect Dis. 2021 Apr;27(4):1196-1200. doi: 10.3201/eid2704.210026. Epub 2021 Feb 4.

Abstract

A concerning development during the coronavirus disease pandemic has been multisystem inflammatory syndrome in children. Reports of this condition in East Asia have been limited. In South Korea, 3 cases were reported to the national surveillance system for multisystem inflammatory syndrome in children. All case-patients were hospitalized and survived with no major disease sequelae.

Keywords: COVID-19; Coronavirus disease; MIS-C; SARS-CoV-2; South Korea; child; inflammation; multisystem inflammatory syndrome; pediatric; respiratory infections; severe acute respiratory syndrome coronavirus 2; surveillance; viruses; zoonoses.

MeSH terms

  • Adolescent
  • COVID-19* / blood
  • COVID-19* / complications
  • COVID-19* / diagnosis
  • COVID-19* / epidemiology
  • COVID-19* / physiopathology
  • COVID-19* / therapy
  • Child
  • Diagnosis, Differential
  • Diarrhea* / diagnosis
  • Diarrhea* / virology
  • Exanthema / diagnosis
  • Exanthema / etiology
  • Female
  • Hospitalization
  • Humans
  • Leukocytosis / diagnosis
  • Leukocytosis / etiology
  • Male
  • Mitral Valve Insufficiency / diagnosis
  • Mitral Valve Insufficiency / etiology
  • Pleural Effusion* / diagnosis
  • Pleural Effusion* / etiology
  • Republic of Korea / epidemiology
  • SARS-CoV-2* / isolation & purification
  • SARS-CoV-2* / pathogenicity
  • Systemic Inflammatory Response Syndrome* / blood
  • Systemic Inflammatory Response Syndrome* / diagnosis
  • Systemic Inflammatory Response Syndrome* / physiopathology
  • Systemic Inflammatory Response Syndrome* / therapy
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome
  • Ultrasonography / methods
  • Ventricular Dysfunction, Left / diagnosis
  • Ventricular Dysfunction, Left / etiology

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related