LC-MS Data set on the Malayan Deer (Cervus timorensis) Antler Velvet and its antibiofilm activity against Candida species: LC-MS Data set on the Malayan Deer (Cervus timorensis) Antler Velvet and its antibiofilm properties against Candida species

Mohd Hafiz Arzmi; Akbar John; Nurul Alia Risma Rismayuddin; Norzaiti Mohd Kenali; Deny Susanti Darnis

doi:10.1016/j.dib.2021.106769

LC-MS Data set on the Malayan Deer (Cervus timorensis) Antler Velvet and its antibiofilm activity against Candida species: LC-MS Data set on the Malayan Deer (Cervus timorensis) Antler Velvet and its antibiofilm properties against Candida species

Data Brief. 2021 Jan 16:35:106769. doi: 10.1016/j.dib.2021.106769. eCollection 2021 Apr.

Authors

Mohd Hafiz Arzmi^{1

2}, Akbar John³, Nurul Alia Risma Rismayuddin², Norzaiti Mohd Kenali⁴, Deny Susanti Darnis⁵

Affiliations

¹ Department of Fundamental Dental & Medical Sciences, Kulliyyah of Dentistry, International Islamic University Malaysia, 25200 Kuantan, Pahang, Malaysia.
² Cluster of Cancer Research Initiative IIUM (COCRII), International Islamic University Malaysia, 25200 Kuantan, Pahang, Malaysia.
³ Department of Biotechnology, Kulliyyah of Science, International Islamic University Malaysia, 25200 Kuantan, Pahang, Malaysia.
⁴ Department of Paediatric Dentistry & Dental Public Health, Kulliyyah of Dentistry, International Islamic University Malaysia, 25200 Kuantan, Pahang, Malaysia.
⁵ Department of Chemistry, Kulliyyah of Science, International Islamic University Malaysia, 25200 Kuantan, Pahang, Malaysia.

Abstract

Deer antler velvet (DAV) has been traditionally used in Chinese medicine, including treatment on toothache [1]. Due to its rapid and regenerative capacity, deer antlers were proposed to be the good model for bone remodelling in mammals [2]. The data presented in this work is on the liquid chromatography and mass spectrometry (LC-MS) profile and bioactive potential of Malayan deer antler velvet (DAV) on different Candida species that has clinical importance. Aqueous extraction of DAV samples was subjected to Liquid chromatography quadrupole time of flight mass spectrometry (LC-QTOF-MS) profiling. Reverse phase (RP) separation was used due to the process extraction using water as a solvent to separate polar compound. The data was interpreted using Profile Analysis 2.1V. The DAV samples were also tested for the effect on the biofilm formation of seven Candida species in a 96 well plate [3]. The biofilms were developed for 72 h in aerobic environment. Following that, the biofilms biomass was determined using crystal violet assay.

Keywords: Candida; Cervus timorensis; DAV; Deer Antler; Malayan deer; Oral treatment.