A rare case of urachal inflammatory myofibroblastic tumor

Rose George; Daniel Swerdloff; Mahmut Akgul; Tipu Nazeer; Badar M Mian

doi:10.1016/j.eucr.2021.101575

A rare case of urachal inflammatory myofibroblastic tumor

Urol Case Rep. 2021 Jan 20:36:101575. doi: 10.1016/j.eucr.2021.101575. eCollection 2021 May.

Authors

Rose George¹, Daniel Swerdloff², Mahmut Akgul¹, Tipu Nazeer¹, Badar M Mian²

Affiliations

¹ Department of Pathology, Albany Medical Center, Albany, NY, 12208, USA.
² Department of Urology, Albany Medical Center, Albany, NY, 12208, USA.

Abstract

Inflammatory myofibroblastic tumors (IMT) of the urachus is a rare neoplastic condition characterized by proliferation of spindle cell, likely derived from myofibroblasts or fibroblasts, with acute and chronic inflammatory infiltrate. Urachal IMT present with abdominal/pelvic pain and urinary symptoms. These often manifest as abdominal mass involving adjacent structures. We describe a case of young female with urachal IMT that was excised with a wide margin to ensure complete removal of all adjacent affected tissue using robotic-assisted laparoscopic approach. Immunohistochemical evidence of ALK and ALK gene rearrangement were confirmed in this tumor which are diagnostic of IMT.

Keywords: Anaplastic lymphoma kinase (ALK); Genitourinary; Inflammatory myofibroblastic tumor (IMT); Urachal.

Publication types

Case Reports