Patterns of thromboembolic pulmonary vascular disease in COVID-19

Yousef Shahin; Smitha Rajaram; Vivak Parkash; James M Wild; David G Kiely; Andrew J Swift

doi:10.1177/2045894020979198

Patterns of thromboembolic pulmonary vascular disease in COVID-19

Pulm Circ. 2021 Jan 21;11(1):2045894020979198. doi: 10.1177/2045894020979198. eCollection 2021 Jan-Mar.

Authors

Yousef Shahin^{1

2}, Smitha Rajaram², Vivak Parkash¹, James M Wild^{1

3}, David G Kiely^{1

4}, Andrew J Swift^{1

2

3}

Affiliations

¹ Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
² Department of Clinical Radiology, Sheffield Teaching Hospitals, Sheffield, UK.
³ INSIGNEO, Institute for In Silico Medicine, University of Sheffield, UK.
⁴ Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK.

Abstract

SARS-CoV-2 (COVID-19) is associated with increased thrombosis. Here, we demonstrate patterns of pulmonary vascular disease in COVID-19 including classical acute pulmonary embolism and subsegmental perfusion defects in the absence of acute pulmonary embolism suggestive of microvascular thrombosis.

Keywords: CT-LSIM; coronavirus; iodine subtraction mapping; microvascular thrombosis; pulmonary embolism.

Abstract

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