BCL11B Regulates Arterial Stiffness and Related Target Organ Damage

Circ Res. 2021 Mar 19;128(6):755-768. doi: 10.1161/CIRCRESAHA.120.316666. Epub 2021 Feb 3.

Abstract

[Figure: see text].

Keywords: actins; blood pressure; calcineurin; phosphorylation; vascular smooth muscle; vascular stiffness.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actins / metabolism
  • Adolescent
  • Adult
  • Animals
  • Aorta / cytology
  • Aorta / metabolism
  • Aorta / physiology
  • Calcineurin / metabolism
  • Cell Adhesion Molecules / metabolism
  • Cell Line
  • Cells, Cultured
  • Cyclic GMP-Dependent Protein Kinase Type I / metabolism
  • Humans
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Microfilament Proteins / metabolism
  • Muscle, Smooth, Vascular / cytology
  • Muscle, Smooth, Vascular / metabolism*
  • Muscle, Smooth, Vascular / physiology
  • Myocytes, Smooth Muscle / metabolism
  • Phosphoproteins / metabolism
  • Repressor Proteins / genetics
  • Repressor Proteins / metabolism*
  • Tumor Suppressor Proteins / genetics
  • Tumor Suppressor Proteins / metabolism*
  • Vascular Stiffness*

Substances

  • Actins
  • Bcl11b protein, mouse
  • Cell Adhesion Molecules
  • Microfilament Proteins
  • Phosphoproteins
  • Repressor Proteins
  • Tumor Suppressor Proteins
  • vasodilator-stimulated phosphoprotein
  • Cyclic GMP-Dependent Protein Kinase Type I
  • Calcineurin