Emergence of myasthenia gravis in dengue infection-first case report

J Neurovirol. 2021 Feb;27(1):183-185. doi: 10.1007/s13365-021-00950-8. Epub 2021 Feb 2.

Abstract

The association of dengue infection (DI) with atypical neurological manifestations was first reported in 1976. DENV-2 and DENV-3 serotypes are mostly related to neurological problems. DI has shown an overall risk of 21 autoimmune diseases, and 4% may develop neuromuscular complications. The pathogenetic mechanisms behind myasthenia gravis (MG) occurring during DI is thought to be linked to the neurotrophic effect of the infection. We report a unique case of DENV-1 infection presenting with bilateral ptosis and dysphagia in a previously healthy adult.

Keywords: Autoimmune disease; Dengue infection; Myasthenia gravis; Serum acetylcholine receptor antibody.

Publication types

  • Case Reports

MeSH terms

  • Dengue / complications*
  • Female
  • Humans
  • Myasthenia Gravis / virology*
  • Young Adult