Blautia-a new functional genus with potential probiotic properties?

Xuemei Liu; Bingyong Mao; Jiayu Gu; Jiaying Wu; Shumao Cui; Gang Wang; Jianxin Zhao; Hao Zhang; Wei Chen

doi:10.1080/19490976.2021.1875796

Blautia-a new functional genus with potential probiotic properties?

Gut Microbes. 2021 Jan-Dec;13(1):1-21. doi: 10.1080/19490976.2021.1875796.

Authors

Xuemei Liu^{1

2}, Bingyong Mao^{1

2}, Jiayu Gu^{1

2}, Jiaying Wu^{1

2}, Shumao Cui^{1

2}, Gang Wang^{1

2}, Jianxin Zhao^{1

2}, Hao Zhang^{1

2

3}, Wei Chen^{1

2

3

4}

Affiliations

¹ State Key Laboratory of Food Science and Technology, Jiangnan University , Wuxi, Jiangsu, China.
² School of Food Science and Technology, Jiangnan University , Wuxi, Jiangsu, China.
³ National Engineering Research Center for Functional Food, Jiangnan University , Wuxi, Jiangsu, China.
⁴ Beijing Innovation Center of Food Nutrition and Human Health, Beijing Technology and Business University (BTBU) , Beijing, China.

Abstract

Blautia is a genus of anaerobic bacteria with probiotic characteristics that occur widely in the feces and intestines of mammals. Based on phenotypic and phylogenetic analyses, some species in the genera Clostridium and Ruminococcus have been reclassified as Blautia, so to date, there are 20 new species with valid published names in this genus. An extensive body of research has recently focused on the probiotic effects of this genus, such as biological transformation and its ability to regulate host health and alleviate metabolic syndrome. This article reviews the origin and biological characteristics of Blautia and the factors that affect its abundance and discusses its role in host health, thus laying a theoretical foundation for the development of new functional microorganisms with probiotic properties.

Keywords: Blautia; biotransformation; host health; probiotics.

Publication types

Review

MeSH terms

Animals
Biotransformation
Clostridiales / classification*
Clostridiales / physiology*
Gastrointestinal Microbiome
Genomics
Humans
Inflammation / microbiology
Metabolic Syndrome / microbiology
Phylogeny
Probiotics*

Grants and funding

This work was supported by National Natural Science Foundation of China (Grant No. 31972086, 31801530), National First-Class Discipline Program of Food Science and Technology (JUFSTR20180102) and Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province.