Vitamin D - current stage of knowledge about analysis and supplementation

Crit Rev Food Sci Nutr. 2022;62(17):4607-4621. doi: 10.1080/10408398.2021.1877110. Epub 2021 Feb 1.

Abstract

Nowadays, topics related to the proper nutrition of the body, which requires a complex of compounds and supplementation of these ingredients have undoubtedly gained popularity, so it should come as no surprise that there is a widespread interest in vitamin D in science, medicine, analytics and nutrition. In the world of developing technologies, new directions of physiological action of this vitamin on the body are being discovered. Issues related to the demand for vitamin D in various populations and its sources in food, the appropriate form of supplementation, safety and toxicity are extremely important. The present manuscript focuses on the concise evaluation of key data in the field of vitamin D. Structure and physicochemical properties, demand and delivery trails, deficiency and its diagnosis, supplementation, interactions of vitamin D with supplements and drugs are discussed. Attention has also been paid to the methods of vitamin D analysis in various matrices, which allow for an accurate and precise quality assessment of dietary supplements, drugs and food products. The presented information allows deeper understanding of the mechanisms responsible for the development of many diseases in the context of vitamin D levels.

Keywords: Vitamin D; analytical methods; quantification; supplementation.

MeSH terms

  • Dietary Supplements
  • Humans
  • Nutritional Status
  • Vitamin D Deficiency*
  • Vitamin D*
  • Vitamins

Substances

  • Vitamins
  • Vitamin D