Triazine-Based Janus G-C Nucleobase as a Building Block for Self-Assembly, Peptide Nucleic Acids, and Smart Polymers

J Org Chem. 2021 Feb 19;86(4):3186-3195. doi: 10.1021/acs.joc.0c02530. Epub 2021 Feb 1.

Abstract

This communication reports on the utility of a triazine-based self-assembling system, reminiscent of a Janus G-C nucleobase, as a building block for developing (1) supramolecular polymers, (2) peptide nucleic acids (PNAs), and (3) smart polymers. The strategically positioned self-complementary triple H-bonding arrays DDA and AAD facilitate efficient self-assembly, leading to a linear supramolecular polymer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Peptide Nucleic Acids*
  • Polymers
  • Stimuli Responsive Polymers*
  • Triazines

Substances

  • Peptide Nucleic Acids
  • Polymers
  • Stimuli Responsive Polymers
  • Triazines