The neurological significance of COVID-19: Lesson learn from the pandemic

Interdiscip Neurosurg. 2020 Dec:22:100809. doi: 10.1016/j.inat.2020.100809. Epub 2020 Jun 17.

Abstract

Coronavirus Infectious Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; previously known as 2019 novel coronavirus) is an emerging and rapidly evolving health issue that has been widespread globally and become a pandemic. The typical symptoms of COVID-19 are: a cough, shortness of breath and a fever; from the initial estimates, about 15% of COVID-19 patients present with severe respiratory symptoms and requires hospitalization and intensive care. Recent accumulated evidences showed that the neurological insults also occurred in patients with COVID-19, ranging from mild headache to severe neurological symptoms. In this review, we summarize the COVID-19 and neurological significance of COVID-19.

Keywords: ACE2, Angiotensin converting enzyme 2; ADEM, Acute disseminated encephalomyelitis; ANE, Acute necrotizing encephalopathy; ARDS, Acute respiratory distress syndrome; CNS, Central nervous system; COVID-19 complications; COVID-19, Coronavirus Infectious Disease 2019; Coronavirus; IL, Interleukin; MOF, Multiple organs failure; Neurological significance; SARS-CoV, Severe acute respiratory coronavirus syndrome; SARS-CoV-2, Severe acute respiratory coronavirus 2 syndrome; SARS-Cov-2.

Publication types

  • Review