Association of Physical Activity and Physical Functioning Phenotypes With Fall Risk Among Women

J Aging Health. 2021 Jun-Jul;33(5-6):409-417. doi: 10.1177/0898264320988405. Epub 2021 Jan 31.

Abstract

Objective: Physical activity (PA) may slow aging-related declines in physical functioning (PF), but the relationship of PA and falls is not well understood. This study examined the association of PA and PF with falls. Methods: The Study of Women's Health Across the Nation participants (n = 1597; age: 65.1 years ± 2.7) reported PF and PA in 2012-2013 and falls in 2016-2017. Four phenotypes were identified: high PA-high PF, high PA-low PF, low PA-high PF, and low PA-low PF. Results: One-third (29.3%) reported ≥1 fall. Women with low PA-low PF (RR = 1.32; 95% CI: 1.06, 1.66) and with high PA-low PF (RR = 1.37; 95% CI: 1.07, 1.74) were more likely to fall than high PA-high PF. Over time, women with worsening PF had increased fall risk (RR = 1.43; 95% CI: 1.17, 1.74), but women who increased PA did not. Discussion: Poor PF increases the risk of falls, regardless of PA. However, increasing PA does not necessarily increase fall risk, reinforcing the importance of PA engagement.

Keywords: falls; physical activity; physical functioning.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Aging*
  • Exercise*
  • Female
  • Humans
  • Phenotype
  • Women's Health