Challenges of diagnostic genomics in Latin America

Curr Opin Genet Dev. 2021 Feb:66:101-109. doi: 10.1016/j.gde.2020.12.010. Epub 2021 Jan 28.

Abstract

Cancer genome sequencing methods have now become essential for diagnostic purposes, for devising treatment strategies, and for monitoring disease regression and progression. However, access to these benefits has not permeated homogeneously throughout the world; certain regions, such as Latin America, have been slower at adopting these technologies in terms of their routine use, development and patient access. There are also differences among Latin American subregions with respect to their prioritized types of neoplasia and the drugs that are available and approved in them. An overview of the current situation, including the status of genomics for cancer diagnostics and efforts by type of cancer is presented. In addition, we discuss the perspective of initiatives, alliances, and educational/research programs that pledge to make cancer genomics diagnosis a reality for Latin American individuals' health.

Publication types

  • Review

MeSH terms

  • Early Detection of Cancer*
  • Genome, Human / genetics*
  • Genomics*
  • Humans
  • Latin America
  • Neoplasms / diagnosis
  • Neoplasms / epidemiology
  • Neoplasms / genetics*
  • Whole Genome Sequencing