The problem of solving linear equations is considered as one of the fundamental problems commonly encountered in science and engineering. In this article, the complex-valued time-varying linear matrix equation (CVTV-LME) problem is investigated. Then, by employing a complex-valued, time-varying QR (CVTVQR) decomposition, the zeroing neural network (ZNN) method, equivalent transformations, Kronecker product, and vectorization techniques, we propose and study a CVTVQR decomposition-based linear matrix equation (CVTVQR-LME) model. In addition to the usage of the QR decomposition, the further advantage of the CVTVQR-LME model is reflected in the fact that it can handle a linear system with square or rectangular coefficient matrix in both the matrix and vector cases. Its efficacy in solving the CVTV-LME problems have been tested in a variety of numerical simulations as well as in two applications, one in robotic motion tracking and the other in angle-of-arrival localization.