A novel hybrid construction of MnMoO4 nanorods anchored graphene nanosheets; an efficient electrocatalyst for the picomolar detection of ecological pollutant ornidazole in water and urine samples

Krishnan Venkatesh; Ramachandran Rajakumaran; Shen-Ming Chen; Chelladurai Karuppiah; Chun-Chen Yang; Sayee Kannan Ramaraj; Mohammad Ajmal Ali; Fahad M A Al-Hemaid; Mohammad Suliman El-Shikh; B M A Almunqedhi

doi:10.1016/j.chemosphere.2021.129665

A novel hybrid construction of MnMoO₄ nanorods anchored graphene nanosheets; an efficient electrocatalyst for the picomolar detection of ecological pollutant ornidazole in water and urine samples

Chemosphere. 2021 Jun:273:129665. doi: 10.1016/j.chemosphere.2021.129665. Epub 2021 Jan 18.

Affiliations

¹ PG and Research Department of Chemistry, Thiagarajar College, Madurai, Tamil Nadu, India.
² Electroanalysis and Bioelectrochemistry Lab, Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei, 106, Taiwan, ROC.
³ Electroanalysis and Bioelectrochemistry Lab, Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei, 106, Taiwan, ROC. Electronic address: smchen78@ms15.hinet.net.
⁴ Department of Chemical Engineering, Ming Chi University of Technology, New Taipei City, 24301, Taiwan, ROC.
⁵ PG and Research Department of Chemistry, Thiagarajar College, Madurai, Tamil Nadu, India. Electronic address: sayeekannanramaraj@gmail.com.
⁶ Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.

PMID: 33508687
DOI: 10.1016/j.chemosphere.2021.129665

Abstract

Nitroimidazole compounds are widely used antibiotics to encounter anaerobic bacterial and parasitic infections. The wide usage of antibiotic drugs became an ecological contaminant which in turn into potential monitoring. In this regards, we have designed and developed a new electrochemical sensing probe to monitor an antiprotozoal drug, ornidazole (ODZ), with the aid of a glassy carbon electrode (GCE) integrated with manganese molybdate nanorods (MnMoO₄) decorated graphene nanosheets (GNS) hybrid materials that prepared by feasible probe sonochemical method (parameters: 2-4 W, 5 mV amp, 20 kHz). The electrochemical investigations of the developed probe were performed by using rapid scan electrochemical workstations namely cyclic voltammetry (CV) and amperometric (i-t) techniques. The as-prepared MnMoO₄/GNS nanocomposite was characterized and its purity of nanocomposite formation was confirmed by various analytical techniques like X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), and Raman spectroscopy. In addition to that, the textural morphology of the MnMoO₄/GNS nanocomposite was examined with the aid of field emission scanning electron microscopy (FE-SEM) and high-resolution transmission electron microscopy (HR-TEM). The MnMoO₄/GNS nanocomposite rotating disk glassy carbon electrode (RDGCE) plays a crucial role in electrochemical detection of ODZ, which results in excellent anti-interference ability, a lower detection limit of 845 pM, massive linear ranges from 10 to 770 nM, and good sensitivity of about 104.62 μA μM^-1 cm^-2. From the acquired electrochemical studies, we have developed a disposable electrochemical sensor probe using a low-cost screen-printed carbon electrode (SPCE) with MnMoO₄/GNS nanocomposite. The MnMoO₄/GNS/SPCE are capably employed in real-time sensing of ODZ in water and urine samples. These electrochemical studies revealed the integral new vision on the electrocatalytic performance of the modified SPCE and also shown excellent amplification results in ultra-trace levels.

Keywords: Electrochemical sensor; MnMoO(4)/Graphene nanocomposite; Ornidazole detection; Real-time analysis; Water and biological samples.

MeSH terms

Electrochemical Techniques
Environmental Pollutants*
Graphite*
Nanotubes*
Ornidazole*
Spectroscopy, Fourier Transform Infrared
Water

Substances

Environmental Pollutants
Water
Ornidazole
Graphite