Biocompatible and functional inorganic magnesium ceramic particles for biomedical applications

Biomater Sci. 2021 Mar 21;9(6):1903-1923. doi: 10.1039/d0bm01934h. Epub 2021 Jan 28.

Abstract

Magnesium ceramics hold promise for numerous biological applications. This review covers the synthesis of magnesium ceramic particles with specific morphologies and potential modification techniques. Magnesium ceramic particles possess multiple characteristics directly applicable to human biology; they are anti-inflammatory, antibacterial, antiviral, and offer anti-cancer effects. Based on these advantages, magnesium hydroxide nanoparticles have been extensively utilized across biomedical fields. In a vascular stent, the incorporation of magnesium ceramic nanoparticles enhances re-endothelialization. Additionally, tissue regeneration for bone, cartilage, and kidney can be promoted by magnesium ceramics. This review enables researchers to identify the optimum synthetic conditions to prepare magnesium ceramics with specific morphologies and sizes and select the appropriate modification protocols. It is also intended to elucidate the desirable physicochemical properties and biological benefits of magnesium ceramics.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents
  • Biocompatible Materials
  • Ceramics
  • Humans
  • Magnesium*
  • Nanoparticles*

Substances

  • Anti-Bacterial Agents
  • Biocompatible Materials
  • Magnesium