Streptococcus pneumoniae Meningitis and Intracranial Vasculopathy: Clinical Correlation with Improving Transcranial Doppler Hemodynamics

Mohamad Imran Idris; Sharon Mei Ling Tai; Chong Tin Tan; Kay Sin Tan

doi:10.1159/000500950

Streptococcus pneumoniae Meningitis and Intracranial Vasculopathy: Clinical Correlation with Improving Transcranial Doppler Hemodynamics

Case Rep Neurol. 2020 Dec 14;12(Suppl 1):106-109. doi: 10.1159/000500950. eCollection 2020 Sep-Dec.

Authors

Mohamad Imran Idris¹, Sharon Mei Ling Tai¹, Chong Tin Tan¹, Kay Sin Tan¹

Affiliation

¹ Division of Neurology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Abstract

Streptococcus pneumoniae are Gram-positive bacteria that are responsible for many types of illnesses including pneumonia, sinus infections, and community-acquired meningitis. One important complication of bacterial meningitis is intracranial vasculopathy. Possible etiologies include vasculitis, vasospasm, endocarditis, or intra-arterial thrombosis. We present a case report of S. pneumoniae meningitis treated with antibiotics in which clinical improvement correlated with serial transcranial Doppler ultrasonography (TCD) improvement, suggesting vasospasm or vasculitis as a possible mechanism for intracranial vasculopathy.

Keywords: Meningitis; Streptococcus pneumoniae; Transcranial Doppler.

Publication types

Case Reports