A History of Diagnostic Investigations in Epilepsy Surgery

Can J Neurol Sci. 2021 Nov;48(6):845-851. doi: 10.1017/cjn.2021.16. Epub 2021 Jan 28.

Abstract

Epilepsy surgery has progressed significantly in the last 150 years. Functional brain maps allowed for the localization of epileptogenic lesions based on seizure patterns, allowing surgeons like McEwan and Horsely to treat epilepsy surgically. Berger's electroencephalogram marked the first modality directly identifying epileptic abnormalities. Penfield and Jasper collaborated, as neurosurgeon and neurologist, to use EEG for surgery. Meanwhile, Wada developed the amobarbital test, improving the protection of language and memory. Talairach and Bancaud pioneered invasive monitoring of deep brain activity with stereoelectroencephalography before the computer age made CT and MRI possible. Looking forward, AI and robotics hold promise for further improving outcomes.

Keywords: Diagnostic investigations; Epilepsy surgery; History of neurosurgery.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brain / diagnostic imaging
  • Brain / surgery
  • Brain Mapping
  • Electroencephalography
  • Epilepsy* / diagnostic imaging
  • Epilepsy* / surgery
  • Humans
  • Stereotaxic Techniques