A new triterpenoids from Nothotsuga longibracteata

J Asian Nat Prod Res. 2021 Dec;23(12):1204-1209. doi: 10.1080/10286020.2020.1870960. Epub 2021 Jan 27.

Abstract

A new lanostane triterpenoid (1) and two known (2, 3) analogues were isolated from Nothotsuga longibracteata. Their chemical structures were identified by spectral data including HR-ESI-MS, 1 D, and 2 D NMR. These lanostane triterpenoids showed no cytotoxic activities against three human tumour cell lines (A172, SHSY5Y, and Hela), but exhibited the activity of promoting the gastrointestinal motility of zebrafish treated with Nile red.

Keywords: Nothotsuga longibracteata; Pinaceae; gastrointestinal motility; lanostane triterpenoid.

MeSH terms

  • Animals
  • Cell Line, Tumor
  • Ganoderma*
  • Humans
  • Molecular Structure
  • Triterpenes* / pharmacology
  • Zebrafish

Substances

  • Triterpenes