Ocular Manifestations of Inflammatory Bowel Disease

Inflamm Bowel Dis. 2021 Oct 20;27(11):1832-1838. doi: 10.1093/ibd/izaa359.

Abstract

Inflammatory bowel disease (IBD) is characterized by intestinal inflammation; however, it is also known to have extraintestinal manifestations. Ocular manifestations of IBD include keratopathy, episcleritis, scleritis, and uveitis and are among the most common extraintestinal manifestations. These diseases can lead to significant ocular morbidity if unrecognized and left untreated. A review of the literature was performed on PubMed and is summarized and critically appraised in this article with the aim being to describe the varying ocular manifestations of IBD and outlining their treatments. Ultimately, a framework is provided to investigate ocular symptoms in patients with IBD. An ocular review of systems is also provided as a tool to equip gastroenterologists and internal medicine physicians to be able to recognize and triage ocular complaints appropriately.

Keywords: episcleritis; inflammatory bowel disease; keratopathy; ocular; ophthalmic; scleritis; uveitis.

Publication types

  • Review

MeSH terms

  • Chronic Disease
  • Humans
  • Inflammatory Bowel Diseases* / complications
  • Scleritis* / diagnosis
  • Scleritis* / etiology
  • Uveitis* / diagnosis
  • Uveitis* / etiology