Long-term cyclic use of a sample collector for toilet-based urine analysis

Mikail Temirel; Bekir Yenilmez; Savas Tasoglu

doi:10.1038/s41598-021-81842-z

Long-term cyclic use of a sample collector for toilet-based urine analysis

Sci Rep. 2021 Jan 26;11(1):2170. doi: 10.1038/s41598-021-81842-z.

Authors

Mikail Temirel^#¹, Bekir Yenilmez^#², Savas Tasoglu^{3

4

5

6}

Affiliations

¹ Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269, USA.
² Department of Mechanical Engineering, University of Connecticut, Storrs, CT, 06269, USA.
³ Department of Mechanical Engineering, Koç University, 34450, Sariyer, Istanbul, Turkey. stasoglu@ku.edu.tr.
⁴ Boğaziçi Institute of Biomedical Engineering, Boğaziçi University, 34684, Çengelköy, Istanbul, Turkey. stasoglu@ku.edu.tr.
⁵ Koç University Arçelik Research Center for Creative Industries (KUAR), Koç University, 34450, Sariyer, Istanbul, Turkey. stasoglu@ku.edu.tr.
⁶ Koç University Research Center for Translational Medicine, Koç University, 34450, Sariyer, Istanbul, Turkey. stasoglu@ku.edu.tr.

^# Contributed equally.

Abstract

Urine analysis via a toilet-based device can enable continuous health monitoring, a transformation away from hospital-based care towards more proactive medicine. To enable reliable sample collection for a toilet-attached analyzer, here a novel sample collector is proposed. The applicability of the proposed sample collector is validated for long-term use. Geometric parameters of the 3D-printed sample collector are optimized. The collected and leftover volumes are quantified for a range of urination speeds and design parameters. For long-term cyclic use, the protein concentrations of samples are quantified and the effectiveness of washing the sample collector is assessed.

MeSH terms

Animals
Bathroom Equipment*
Cattle
Equipment Design
Humans
Proteins / analysis
Reproducibility of Results
Specimen Handling / instrumentation*
Urinalysis / instrumentation*

Substances

Proteins